Bun normal range male4/23/2024 ![]() BUN levels often rise when kidneys are not able to remove urea from the blood normally and a BUN test is used to measure kidney function. BUN measures the amount of nitrogen in blood that comes from the waste product urea. Studies have shown that renal function markers, including blood urea nitrogen (BUN), glomerular filtration rate and creatinine, are associated with mortality from CVD ( 4, 5). It is therefore crucial to find biomarkers that can predict the occurrence of CVD so prevention measures can be implemented. It is estimated that China has one of the highest CVD death rates in the world, with one in five adults in China experiencing a cardiovascular disease ( 3). The global prevalence of CVD nearly doubled from 271 million in 1990 to 523 million in 2019, and the number of CVD deaths steadily increased from 12.1 million in 1990, reaching 18.6 million in 2019 ( 2). With economic development and the change of lifestyle, the incidence of CVD in China is rising rapidly. A higher BUN level (>13.51 mg/dL) is associated with an increased occurrence of HF but a decreased occurrence of diabetes and metabolic symptoms in normal older females.Ĭardiovascular disease (CVD) is a global public health problem associated with adverse outcomes ( 1). ![]() No association was found between BUN and CVD in male subjects.Ĭonclusions: Current results indicate that BUN is a valuable predictive biomarker of CVD. The Cox regression analysis found an association between baseline BUN and incident CVD in female subjects, with higher BUN associated with increased risk of AF in females and kidney disease in both male and females. Results: During the follow-up, subjects were newly diagnosed with CVD including heart failure (HF), heart disease events, atrial fibrillation, diabetes, hypertension, metabolic syndrome, and kidney disease. We monitored the occurrence of CVD and explored the relationship between BUN and CVD via a Cox regression analysis. During the follow-up period (2014–2017), the researchers regularly tested the subjects' indicators and assessment scales. In the baseline, subjects were asked to participate in medical screening and biological tests, and answered survey questions. We recruited 5,000 older people among 137,625 residents of the Gaohang community. This study aims to explore the incidence and risk factors of CVD among a healthy older population community in China.ĭesign and Methods: This study was designed as a cohort study with a 4-year follow-up. ![]() However, no study has explored whether BUN can predict the risk of cardiovascular disease (CVD) in the healthy older population. ![]()
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